Hossein Mohammadhassanzadeh

@article{Mohammadhassanzadeh2017,

title = {Semantics-based Plausible Reasoning to Extend the Knowledge Coverage of Medical Knowledge Bases for Improved Clinical Decision Support},

author = {Hossein Mohammadhassanzadeh and William Van Woensel and Samina Raza Abidi and Syed Sibte Raza Abidi},

url = {http://rdcu.be/paPY},

doi = {10.1186/s13040-017-0123-y},

year  = {2017},

date = {2017-02-10},

journal = {Journal of BioData Mining},

volume = {10},

number = {7},

abstract = {Background

Capturing complete medical knowledge is challenging-often due to incomplete patient Electronic Health Records (EHR), but also because of valuable, tacit medical knowledge hidden away in physicians’ experiences. To extend the coverage of incomplete medical knowledge-based systems beyond their deductive closure, and thus enhance their decision-support capabilities, we argue that innovative, multi-strategy reasoning approaches should be applied. In particular, plausible reasoning mechanisms apply patterns from human thought processes, such as generalization, similarity and interpolation, based on attributional, hierarchical, and relational knowledge. Plausible reasoning mechanisms include inductive reasoning, which generalizes the commonalities among the data to induce new rules, and analogical reasoning, which is guided by data similarities to infer new facts. By further leveraging rich, biomedical Semantic Web ontologies to represent medical knowledge, both known and tentative, we increase the accuracy and expressivity of plausible reasoning, and cope with issues such as data heterogeneity, inconsistency and interoperability. In this paper, we present a Semantic Web-based, multi-strategy reasoning approach, which integrates deductive and plausible reasoning and exploits Semantic Web technology to solve complex clinical decision support queries.



Results

We evaluated our system using a real-world medical dataset of patients with hepatitis, from which we randomly removed different percentages of data (5%, 10%, 15%, and 20%) to reflect scenarios with increasing amounts of incomplete medical knowledge. To increase the reliability of the results, we generated 5 independent datasets for each percentage of missing values, which resulted in 20 experimental datasets (in addition to the original dataset). The results show that plausibly inferred knowledge extends the coverage of the knowledge base by, on average, 2%, 7%, 12%, and 16% for datasets with, respectively, 5%, 10%, 15%, and 20% of missing values. This expansion in the KB coverage allowed solving complex disease diagnostic queries that were previously unresolvable, without losing the correctness of the answers. However, compared to deductive reasoning, data-intensive plausible reasoning mechanisms yield a significant performance overhead.



Conclusions

We observed that plausible reasoning approaches, by generating tentative inferences and leveraging domain knowledge of experts, allow us to extend the coverage of medical knowledge bases, resulting in improved clinical decision support. Second, by leveraging OWL ontological knowledge, we are able to increase the expressivity and accuracy of plausible reasoning methods. Third, our approach is applicable to clinical decision support systems for a range of chronic diseases.},

keywords = {Analogical reasoning, Inductive generalization, Medical knowledge bases, Plausible reasoning, Semantic Web reasoning},

pubstate = {published},

tppubtype = {article}

}

@article{Mohammadhassanzadeh2013,

title = {Prediction of User’s Trustworthiness in Web-based Social Networks via Text Mining},

author = {Hossein Mohammadhassanzadeh and Hamid Reza Shahriari},

url = {http://isecure-journal.com/index.php/isecure/article/view/12-163/73},

year  = {2013},

date = {2013-07-01},

journal = {ISecure Journal},

volume = {5},

number = {2},

pages = {171-187},

abstract = {In Social networks, users need a proper estimation of trust in others to be able to initialize reliable relationships. Some trust evaluation mechanisms have been offered, which use direct ratings to calculate or propagate trust values. However, in some web-based social networks where users only have binary relationships, there is no direct rating available. Therefore, a new method is required to infer trust values in these networks. To bridge this gap, this paper aims to propose a new method which takes advantage of user similarity to predict trust values without any need for direct ratings. In this approach, which is based on socio psychological studies, user similarity is calculated from the profile information and the texts shared by the users via text-mining techniques. Applying Ziegler ratios to our approach revealed that users are more than 50% more similar to their trusted agents than to arbitrary peers, which proves the validity of the original idea of the study about inferring trust from language similarity. In addition, comparing the real assigned ratings, gathered directly from users, with the experimental results indicated that the predicted trust values are sufficiently acceptable (with a precision of 61%). We have also studied the benefits of using context in inferring trust. In this regard, the analysis revealed that the precision of the predictions can be improved up to 72%. Besides the application of this approach in web-based social networks, the proposed technique can also be of much help in any direct rating mechanism to evaluate the correctness of trust values assigned by users, and increases the robustness of trust and reputation mechanisms against possible security threats.},

keywords = {Data Mining, Social Network Analysis},

pubstate = {published},

tppubtype = {article}

}